โจรหัวหมอเจาะรูยักษ์ บนผนังคอนกรีต จากร้านข้าง ๆ ขโมยเครื่องประดับมูลค่า 665 ล้านบาท ด้านเจ้าหน้าที่ตำรวจตรวจสอบที่เกิดเหตุเพื่อหาลายนิ้วมือและดีเอ็นเอ
สำนักข่าวต่างประเทศ รายงาน เมื่อเร็ว ๆ นี้ เกิดการโจรกรรมในร้านขายเครื่องประดับแห่งหนึ่งในลอสแอนเจลิส สหรัฐอเมริกา โจรได้ขุดอุโมงค์ผ่านกำแพงคอนกรีตเพื่อเข้าไปในร้านขายเครื่องประดับและสามารถขโมยทรัพย์สินมูลค่าประมาณ 20 ล้านเหรียญสหรัฐ (ประมาณ 665 ล้านบาท)ได้สำเร็จ ซึ่งรวมถึงเงินสด ทองคำ นาฬิกา สร้อยคอ และสิ่งของอื่น
เหตุการณ์เกิดขึ้นเมื่อเวลาประมาณ 21.30 น. ในวันที่ 13 เมษายนที่ผ่านมา ณ ร้านจิวเวลรี่ Love Jewels ที่เลขที่ 500 ถนน South Broadway ในตัวเมืองลอสแอนเจลิส เจ้าหน้าที่ได้ตรวจสอบกล้องวงจรปิด พบว่าคนร้ายได้เข้าไปในร้านผ่านรูขนาดใหญ่บนผนัง และพบอุโมงค์อยู่ในที่เกิดเหตุ พวกเขาคาดเดาว่าขโมยเริ่มขุดอุโมงค์จากโรงละครร้างข้าง ๆ และในที่สุดก็สามารถทะลุผ่านกำแพงอิฐทึบของร้านขายเครื่องประดับได้สำเร็จ
พนักงานร้านขายจิวเวลรี่ไม่ได้รู้ว่าร้านถูกปล้นจนกระทั่งเช้าวันรุ่งขึ้นเมื่อพวกเขามาถึงที่ทำงาน สิ่งของในตู้เซฟทั้ง 2 ใบในร้านถูกปล้นไปหมด ร้านขายจิวเวลรี่กล่าวว่า พวกเขาสงสัยว่าหัวขโมยใช้เวลาอย่างน้อยหนึ่งสัปดาห์ในการค่อยๆ เจาะผนังเข้าไป “พวกเขาอาจจะเข้าไปทุกคืนและขุดช้าๆ จนกว่าอุโมงค์จะใหญ่พอสำหรับพวกเขา”
ผู้ต้องสงสัยออกจากร้านทางช่องเดียวกันและหลบหนีด้วยรถบรรทุกเชฟโรเลต เมื่อเกิดการโจรกรรมขึ้น ไม่มีสัญญาณเตือนภัยดังขึ้นและไม่มีการบันทึกวิดีโอในขณะที่กล้องวงจรปิดในร้านถูกตัดออกอย่างรวดเร็วโดยคนร้าย ซึ่งมีการประเมินความเสียหายสูงถึง 20 ล้านเหรียญสหรัฐ
ลูกชายเจ้าของร้านขายเครื่องประดับเล่าว่า “พ่อของผมใช้เวลา 20 กว่าปีในการสะสมทรัพย์สินเหล่านี้ แต่ทั้งหมดถูกขโมยไปในชั่วข้ามคืน ทรัพย์สินที่ถูกขโมยไปส่วนใหญ่เป็นทองคำและอุปกรณ์เสริมที่เกี่ยวข้อง เราเก็บเงินทั้งหมดไว้ในตู้เซฟ และตอนนี้เราไม่มีอะไรเหลือเลย” เขาสงสัยว่าโจรคนหนึ่งอาจเป็นช่างกุญแจมืออาชีพที่สามารถเปิดตู้เซฟได้อย่างง่ายดาย
นอกจากนี้ ร้านขายจิวเวลรี่ Love Jewels ไม่มีประกันภัย มีการเสนอรางวัลมูลค่า 100,000 เหรียญสหรัฐ (ราว 3.24 ล้านเหรียญไต้หวัน) โดยหวังว่าจะมีใครสามารถช่วยหาเบาะแสได้ คดีนี้อยู่ระหว่างการสอบสวนโดยตำรวจลอสแอนเจลิสและตำรวจรัฐบาลกลาง ซึ่งเจ้าหน้าที่ตำรวจได้ตรวจสอบที่เกิดเหตุเพื่อหาลายนิ้วมือและดีเอ็นเอ
Test And Anavar Cycle Review + Dosage All Test Types
Test And Anavar Cycle
A combined regimen of testosterone and Anavar (oxandrolone)
is popular among bodybuilders and athletes who seek rapid muscle gains while minimizing fat gain and excessive water retention. The cycle
typically lasts 8–12 weeks, with testosterone administered at a moderate dose to support anabolic activity,
and Anavar added later in the cycle to enhance strength and lean mass
without significant estrogenic side effects.
Key Takeaways
Testosterone provides the primary anabolic stimulus for muscle growth.
Anavar adds potent anabolic action while keeping water retention low.
Proper scheduling—starting with testosterone and introducing Anavar
midway—maximizes gains and limits hormonal
disruption.
Post‑cycle therapy (PCT) is essential to restore natural hormone production.
What is Testosterone?
Testosterone is the primary male sex hormone produced mainly in the testes, with smaller amounts from adrenal glands.
It regulates secondary sexual characteristics, libido, bone density, red blood cell production, and overall muscle
mass maintenance.
Types of Testosterone Steroids
Anabolic-only formulations (e.g., testosterone propionate, enanthate,
cypionate).
Combined androgenic‑anabolic steroids that possess both masculinizing
and muscle-building properties.
Injectable esters with varying half-lives, influencing dosing frequency.
How does Testosterone work?
Testosterone binds to androgen receptors in target tissues, triggering
gene expression that increases protein synthesis, nitrogen retention, and
satellite cell activation—key drivers of muscle hypertrophy.
Testosterone Benefits
Increased lean body mass
Enhanced strength and endurance
Improved recovery rates
Mood stabilization and cognitive benefits
Testosterone Side Effects
Common side effects include acne, hair loss, gynecomastia (when aromatized), mood swings,
and potential cardiovascular strain. Long-term use may
suppress natural testosterone production.
TESTO‑MAX
A high‑purity injectable testosterone commonly used in cycles for
its strong anabolic profile.
TESTO‑MAX Overview
Contains 100 mg of testosterone propionate
per vial.
Rapid onset with short half‑life, requiring frequent injections (2–3 times
weekly).
Preferred by users seeking a quick surge in anabolic activity.
What is Anavar?
Anavar, or oxandrolone, is a synthetic anabolic steroid derived from dihydrotestosterone.
It’s renowned for its mild androgenic properties and low
estrogenic potential.
How Does Anavar Work?
Oxandrolone binds to androgen receptors but also increases protein synthesis with less impact on water retention and estrogen conversion, making it ideal for cutting phases or lean mass building.
Anavar Benefits
Significant strength gains without heavy weight load.
Minimal fat gain; often improves definition.
Low risk of gynecomastia compared to other steroids.
Anavar Side Effects
Potential side effects include liver strain (oral form), hormonal
suppression, mood changes, and in rare cases, increased blood pressure or cholesterol disturbances.
ANVAROL
A popular oral formulation of Anavar known for its high bioavailability and potency.
ANVAROL Overview
Typically 20 mg per tablet.
Oral route simplifies dosing but imposes hepatic load.
Users favor it for short cycles where injection compliance
is a concern.
Test and Anavar Cycle
The cycle usually begins with testosterone for the first 4–6 weeks, followed by
adding Anavar in weeks 5–8 to spike strength and
lean mass while maintaining low water retention.
Benefits of Test and Anavar Cycle
Rapid muscle hypertrophy with minimal weight gain.
Enhanced muscular definition due to low edema.
Reduced estrogenic side effects compared to testosterone alone.
Drawbacks of a Testosterone and Anavar Cycle
Hormonal suppression requiring post‑cycle therapy.
Possible liver stress from oral Anavar.
Increased risk of androgenic side effects (hair loss, acne).
Hair Loss
Both testosterone and Anavar can accelerate androgenic alopecia in genetically predisposed individuals due
to dihydrotestosterone activity.
Increase in Blood Pressure
Anabolic steroids may elevate systolic and diastolic pressures; monitoring is advised during
a cycle.
Cholesterol
Steroid use often reduces HDL while increasing LDL,
contributing to cardiovascular strain if not managed with diet or medication.
Kidney Damage
Long‑term anabolic steroid abuse can lead to nephrotoxicity, especially when combined with high protein intake and dehydration practices.
Conclusion: Should I take Anavar with Testosterone?
For athletes seeking lean muscle gains with minimal water retention, a
carefully planned testosterone plus Anavar cycle can be effective.
However, risks—particularly hormonal suppression, cardiovascular
strain, and liver stress—must be weighed against
the benefits. Proper dosing, monitoring, and post‑cycle therapy are essential for safety.
Comments and questions?
Feel free to share your experiences or ask for clarification on specific aspects of steroid cycles, dosage
adjustments, or PCT protocols.
—
The following sections provide additional resources and insights into related topics:
Best Steroids for Sale Online: Your Guide to Safe and Legal Options
When purchasing steroids, look for reputable vendors offering
third‑party lab testing, clear dosage instructions, and discreet shipping.
Most Dangerous Anabolic Steroids
Some compounds carry higher toxicity risks; always
research each steroid’s side‑effect profile before use.
Arimistane Review
A natural aromatase inhibitor that can be used to mitigate estrogenic effects during a
steroid cycle.
Best Prohormone Companies
Prohormones are precursors that convert into anabolic steroids in the body.
Choose suppliers with transparent sourcing and quality control.
PCT for Testosterone Cycle: Your Guide to Reclaiming Natural Levels
Post‑cycle therapy often includes agents such as SERMs or aromatase inhibitors to restore endogenous testosterone production.
Turkesterone vs Ecdysterone
Both are plant-derived anabolic compounds; studies suggest differing potency levels and
side‑effect profiles.
Contributors
Daniel Louwrens BSc PT Writer
Learn More On This Subject…
Dianabol (Metandienone) Effects, Dangers, and Legal Alternatives
Anavar: Side Effects, recommended dosage of anavar for males, Results and Where to Buy
Deca Vs Tren: The Ultimate Showdown
Superdrol Cycle: Dosage, Results And Side effects
Clenbuterol For Women: What Makes It The Best Fat Burner?
The above references provide deeper dives into specific steroids, comparative analyses, and safety guidelines.
More Middle-aged Men Taking Steroids To Look Younger Men’s Health
**The Rise of “Supplement‑First” Choices: Why More People Are
Turning to Nutrient Boosts**
—
### 1. A Growing Shift
Over the past decade, sales data show a steady climb in dietary supplements—multivitamins,
vitamin D3, omega‑3 oils, probiotics and more—while prescriptions for certain nutrients (e.g., vitamin B12 injections) have remained relatively flat.
In grocery aisles and online marketplaces alike, “supplement‑first” kits are becoming as
common as a standard breakfast cereal.
—
### 2. What’s Behind the Trend?
| Driver | Why It Matters |
|——–|—————-|
| **Convenience** | A quick pill or capsule is faster than scheduling a
doctor’s visit for routine checks. |
| **Cost Control** | Many people view supplements
as a cheaper alternative to frequent clinical visits, especially in systems with high co‑pay
structures. |
| **Health Consciousness** | Growing awareness of preventive health
nudges consumers toward self‑management tools.
|
| **Perceived Empowerment** | The idea that “I can take charge” appeals to those wary
of institutional medical authority. |
—
### 3. The Potential Impact on the Health System
1. **Reduced Primary Care Load**
– Routine screening questions (e.g., blood pressure checks, cholesterol levels) may shift from office visits to home monitoring kits.
2. **Risk of Over‑ or Under‑Treatment**
– Without professional oversight, patients might misinterpret results, leading either to unnecessary medication or missed treatment opportunities.
3. **Data Management Challenges**
– Integrating patient‑generated data into electronic health records (EHRs) requires secure pipelines and interoperability standards.
4. **Economic Considerations**
– Short‑term savings from fewer office visits may be offset by costs of monitoring devices,
data storage, and potential adverse events.
### Policy Recommendations
| Recommendation | Rationale | Implementation |
|—————–|———–|—————-|
| **Standardize Monitoring Protocols** | Ensures consistency across
providers and patients. | Develop national guidelines for device use, calibration, and result interpretation.
|
| **Mandate Data Integration Standards** | Facilitates seamless EHR connectivity.
| Adopt HL7 FHIR profiles for patient-generated health data (PGHD).
|
| **Encourage Public‑Private Partnerships** | Leverages innovation while ensuring public oversight.
| Create incentive structures for manufacturers to comply with safety and privacy regulations.
|
| **Invest in Digital Health Literacy Programs** | Empowers patients to use monitoring tools effectively.
| Allocate funding for community workshops, especially targeting underserved populations.
|
| **Establish a Centralized Registry of Devices** | Enhances
traceability and post‑market surveillance.
| Require manufacturers to submit device details to
the FDA’s database. |
These recommendations are grounded in current regulatory frameworks (FDA guidance on medical devices, HIPAA privacy rules) and aim to build upon the successes seen during the COVID‑19 pandemic.
—
### 3. Counterarguments & Rebuttals
| **Counterargument** | **Rebuttal** |
|———————-|————–|
| **Economic Burden** – “The cost of regulating and monitoring an influx of home‑based devices will strain healthcare budgets.” | While upfront costs
exist, the long‑term savings from preventing hospitalizations
(e.g., reduced ICU stays) outweigh regulatory expenses.
Additionally, streamlined processes modeled on rapid pandemic approvals can minimize overhead.
|
| **Technological Inequity** – “Many patients lack access to reliable internet or smartphones; widespread home monitoring would widen disparities.” | Targeted subsidies for broadband and device distribution in underserved communities mitigate this
risk. Moreover, low‑bandwidth solutions (SMS alerts) can be employed where data connectivity
is limited. |
| **Data Overload** – “Clinicians may become overwhelmed by constant patient-generated data.” | Advanced analytics platforms that flag actionable alerts reduce
cognitive load. Integration with existing EMR workflows ensures
clinicians receive distilled information rather than raw streams.
|
—
### 4. Implementation Roadmap
| Phase | Objectives | Key Activities | Success Metrics |
|——-|————|—————-|—————–|
| **Phase 1 – Pilot (Months 0–12)** | Validate system feasibility
and identify gaps | – Deploy in select hospitals with high COVID‑19 census
– Train staff on data collection, EHR integration, analytics dashboards
– Conduct weekly quality checks on data completeness | –
≥80 % of scheduled vitals captured
– Data latency 90 % |
| **Phase 3 – Sustain (Months 24+)** | Institutionalize within hospital systems and maintain data quality | – Embed dashboards into EHR workflows
– Conduct periodic data audits and refresher training
– Update governance policies for evolving regulations | – Continuous audit score ≥95 %
– Governance compliance maintained |
—
### 5. Executive Summary
The proposed system will capture high‑resolution vital sign data from bedside
monitors, automatically process it into clinically meaningful features, and integrate these insights into hospital dashboards to support rapid
decision‑making in acute care settings. By leveraging a modular architecture that separates acquisition, processing, analytics,
and presentation layers, the platform remains flexible and scalable across diverse clinical environments.
Key advantages include:
– **Improved Clinical Outcomes**: Early detection of
physiological deterioration allows timely
interventions.
– **Operational Efficiency**: Automated monitoring reduces manual charting burden on clinicians.
– **Data‑Driven Insights**: Aggregated metrics enable continuous quality improvement
and benchmarking.
– **Regulatory Compliance**: Robust security, audit trails,
and data governance frameworks align with HIPAA and
other standards.
The platform’s design also anticipates future
extensions—such as integrating wearable sensor data or applying machine learning models—to keep
pace with evolving healthcare technologies. By investing in this infrastructure,
health systems can harness the full potential of patient‑centric data to deliver safer, higher‑quality care.
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Oxandrolone Wikipedia
Sodium Oxybate
Sodium oxybate (commercially known as Xanaxil® in some regions) is the sodium salt of
the drug oxycodone’s major metabolite, 3‑hydroxy‑4‑oxo‑2‑methyl‑pyrrolidine-1‑butanoic acid.
It is a short‑acting, centrally acting compound that has gained therapeutic use primarily for two sleep‑disorder conditions:
Indication Typical Clinical Use
Narcolepsy with cataplexy Nighttime dosing to reduce daytime somnolence and improve sleep continuity
Idiopathic hypersomnia (IH) Off‑label nighttime administration to consolidate sleep, reduce excessive daytime sleepiness
The following review synthesizes the current literature
on 3‑hydroxy‑4‑oxo‑2‑methyl‑pyrrolidine‑1‑butanoic acid’s pharmacology,
therapeutic efficacy, and safety profile.
—
Pharmacological Profile
1. Mechanism of Action
While a complete mechanism remains elusive, preclinical studies
indicate that the compound acts as a monoamine reuptake inhibitor with preferential affinity for serotonin (SERT) and norepinephrine transporters (NET).
This results in increased extracellular concentrations of these neurotransmitters, which are implicated in wakefulness
regulation.
Preclinical Evidence: Rat studies show significant inhibition of
SERT at sub‑micromolar concentrations, suggesting a potent serotonergic effect.
NET blockade is weaker but still measurable.
Clinical Correlation: The wake-promoting effects observed clinically
align with increased monoaminergic tone in the central nervous
system.
Alternative Hypotheses:
The compound may also modulate dopamine D2 receptors, contributing to arousal.
It could influence glutamatergic or GABAergic transmission indirectly via
serotonergic pathways.
4. Pharmacokinetics (PK)
Parameter Data
Absorption Rapid oral absorption; peak plasma concentration (Tmax) at ~1–2 h post-dose.
Distribution High plasma protein binding (~90%). Volume of distribution (Vd) ~0.5 L/kg.
Metabolism Primarily hepatic via CYP3A4 oxidation to N-hydroxy metabolite
and further conjugation (glucuronidation). Minor pathways:
CYP2D6, CYP1A2.
Elimination Half-life Approx. 4–6 h (may vary with dose).
Clearance Hepatic clearance predominant; renal excretion minimal (18 yr.
For patients anavar 25mg a day results therapeutic
effect.
By following this framework—choosing the right target, designing a molecule with optimal
potency, selectivity, and drug‑like properties, and rigorously
testing it—you can create a targeted therapy capable of treating disease while minimizing off‑target toxicity.
prolonged steroid use side effects
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Ipamorelin has attracted a lot of attention on Reddit communities that focus on peptide therapy, bodybuilding, and anti‑aging protocols.
Users are often eager to hear about the potential benefits while also wanting realistic information about any adverse reactions they
might experience. Below is an in-depth look at what people are reporting,
how the peptide works, and which side effects appear most frequently.
—
Ipamorelin Side Effects: Unlocking Potential, Balancing Risks
The discussion around ipamorelin on Reddit often centers on a dual narrative: the excitement over its growth hormone‑releasing properties versus caution about the unknown long‑term safety
profile. Many threads emphasize that while short‑term usage is generally well tolerated, there can be subtle side effects that require monitoring.
Why People Are Interested
Growth Hormone Release: Ipamorelin stimulates the pituitary
to secrete growth hormone (GH) without a
significant rise in prolactin or cortisol.
This selective action makes it attractive for users who want
the anabolic benefits of GH but fear the metabolic
side effects associated with other secretagogues.
Lean Muscle Gain and Recovery: Bodybuilders report increased muscle mass, faster
recovery times, and improved joint health after consistent use.
Aging and Wellness: Older Redditors discuss improvements in skin elasticity,
energy levels, and overall vitality.
The Cautionary Side
Limited Clinical Data: Most evidence comes
from small animal studies or short‑term human trials.
Reddit users often cite anecdotal reports rather than peer‑reviewed data.
Potential Hormonal Imbalance: Even though ipamorelin is designed to be selective, some users notice mild increases in appetite or changes in sleep patterns, which may signal hormonal
shifts.
Individual Variability: The same dose that works well for one person can lead to discomfort or more pronounced side effects in another.
What Is Ipamorelin and How Does It Work?
Ipamorelin is a synthetic pentapeptide with the sequence pyroglutamyl‑Glu‑Pro‑His‑Leu.
Its design mimics ghrelin, a stomach hormone that signals hunger and growth
hormone release. Here’s how it operates:
Growth Hormone Secretagogue Receptor (GHSR) Activation
Ipamorelin binds to GHSR-1a on pituitary somatotroph cells.
This binding triggers the release of GH into the bloodstream.
Selective Action
Unlike other secretagogues such as GHRP‑6 or sermorelin, ipamorelin has minimal effects on prolactin and cortisol levels.
This selectivity is why users often report fewer endocrine side effects.
Metabolic Effects
The GH surge stimulates protein synthesis, increases lipolysis
(fat breakdown), and improves insulin sensitivity.
In practice, this translates to lean muscle gain and potential fat loss over time.
Administration Routes
Most Reddit users administer ipamorelin via subcutaneous injections (commonly 200–400 µg per day).
Some opt for intranasal or oral formulations, but these
are less common due to lower bioavailability.
Commonly Reported Side Effects
While many users claim no major adverse reactions after short‑term use, a few side
effects recur across Reddit threads. Below is an organized
list based on user reports:
1. Injection Site Reactions
Pain or Tenderness
A small percentage of users experience mild discomfort at the injection site, especially when injecting
for the first time.
Redness and Swelling
Occasional redness or a slight swelling around the needle track can occur if injections are too frequent or too close together.
2. Appetite Changes
Increased Hunger
Because ipamorelin mimics ghrelin, many users report an uptick
in appetite, often described as a “food craving” that
appears after injection.
Weight Gain (Non‑Muscular)
Some Redditors note slight weight increases, which they attribute to higher
caloric intake rather than fat accumulation.
3. Sleep Disturbances
Insomnia or Restlessness
A minority of users report difficulty falling asleep or a restless night after using ipamorelin late in the day.
Improved Sleep Quality
Conversely, others claim deeper sleep when taking it at night, indicating that responses can be highly
individual.
4. Headaches
Transient Headache
Occasional throbbing headaches have been reported, especially during the first few days of therapy or after dose adjustments.
5. Fatigue and Weakness
Mild Fatigue
Some users feel a low‑grade tiredness, often resolving within a day.
Muscle Weakness
Rarely, individuals report transient muscle weakness, which typically
improves once the body acclimates to the peptide.
6. Hormonal Side Effects (Rare)
Prolactin Elevation
Though uncommon, a handful of Redditors mention elevated prolactin levels in blood tests after prolonged use.
Cortisol Fluctuations
A few users observed slightly higher cortisol readings during stress
testing.
7. Other Miscellaneous Reports
Increased Sweating
Some individuals notice more perspiration, especially when exercising post‑injection.
Skin Breakouts or Acne
Rarely, acne flare-ups have been attributed to hormonal shifts.
Mood Changes
A few users note mild mood swings or irritability that subside after
a few days.
Tips for Minimizing Side Effects
Reddit communities frequently share practical advice:
Start Low, Go Slow – Begin with the lowest effective dose (e.g.,
200 µg) and increase gradually if tolerated.
Inject Properly – Rotate injection sites
to avoid lipodystrophy or chronic inflammation.
Time Your Dose – Many users prefer morning injections
to reduce appetite spikes during the day.
Monitor Hormones – Periodic blood tests for GH, prolactin, and cortisol can help catch any imbalances early.
Hydration & Nutrition – Adequate water intake and balanced
meals may mitigate headaches and fatigue.
Bottom Line
Ipamorelin’s appeal on Reddit stems from its selective growth hormone‑releasing properties and relatively low
incidence of major side effects compared to other secretagogues.
Most users report only mild, transient reactions such as
injection site discomfort, appetite changes,
or occasional headaches. Nonetheless, individual responses vary
widely, and the lack of extensive long‑term data means caution is advised.
By starting with a conservative dose, following proper injection technique, and
monitoring for any hormonal shifts, many Reddit participants
find that ipamorelin can be incorporated safely into their wellness or training regimens while keeping side effects to a minimum.
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